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The next is a abstract of some current research on COVID-19. They embody analysis that warrants additional research to corroborate the findings and that has but to be licensed by peer overview.
Publish-infection vaccination might scale back lengthy COVID
Vaccination after an infection with SARS-CoV-2 might contribute to a discount within the burden of lengthy COVID signs, a brand new research suggests.
Researchers tracked 6,729 volunteers ages 18 to 69, who bought two pictures of both AstraZeneca’s AZN.L viral vector vaccine or an mRNA vaccine from Pfizer PFE.N/BioNTech 22UAy.DE or Moderna MRNA.O after recovering from an an infection with the coronavirus and who reported lengthy COVID signs of any severity not less than as soon as between February and September 2021.
The chances of reporting lengthy COVID – signs lasting not less than 12 weeks – fell by a median of 13% after a primary vaccine dose, the researchers reported on Wednesday in The BMJ.
The second dose, given 12 weeks after the primary, was related to an additional 9% lower within the odds of lengthy COVID that persevered for not less than 9 weeks, on common, the researchers mentioned. The chances of reporting lengthy COVID extreme sufficient to lead to practical impairment had been equally decreased, researchers reported.
Outcomes had been related no matter vaccine sort, interval from an infection to first vaccine dose, underlying well being standing, or severity of COVID-19. Nonetheless, the research was not designed to detect such variations, nor can it definitively show that vaccines decrease the percentages of lengthy COVID.
“Additional analysis is required to guage the long-term relationship between vaccination and lengthy COVID, specifically the influence of the Omicron variant,” which emerged after this research ended, the researchers mentioned.
Desktop “air curtains” might deflect virus particles
When individuals can’t keep a protected distance to keep away from the unfold of COVID-19, a newly designed desktop “air curtain” can block aerosols in exhaled air, researchers discovered.
Air-curtains – artificially created streams of transferring air – are sometimes used to guard sufferers in working rooms. At Nagoya College in Japan, researchers examined their new desktop machine by simulating a blood assortment sales space through which a lab technician is near the affected person.
Aerosol particles blown towards the curtain “had been noticed to bend abruptly towards (a) suction port” with out passing by way of the air curtain, they reported on Tuesday in AIP Advances.
Even placing an arm by way of the air curtain didn’t break the circulate or scale back its effectiveness, they mentioned. A high-efficiency particulate air (HEPA) filter may be put in contained in the suction port, they added.
If additional testing in real-life situations confirms the effectiveness of the system, it may “be helpful as an oblique barrier not solely within the medical discipline but in addition in conditions the place ample bodily distance can’t be maintained, equivalent to on the reception counter,” the researchers mentioned.
Antacid aids in COVID-19 by serving to restrict irritation
Researchers have found simply how the antacid famotidine, generally offered as Pepcid by a Johnson & Johnson JN.N unit, was in a position to assist alleviate COVID-19 signs in scientific trials.
In research in mice, they discovered that famotidine stimulates the vagus nerve, which controls the immune system and different involuntary physique capabilities.
When the vagus nerve is stimulated, it might ship out alerts to suppress extreme immune reactions – so-called cytokine storms – through which excessive ranges of inflammatory proteins are launched into the blood too rapidly.
When famotidine was administered to the mice, it considerably decreased ranges of inflammatory proteins within the blood and spleen and improved survival. However when the vagus nerve was minimize, famotidine not stopped the cytokine storms, in keeping with a report revealed on Monday in Molecular Drugs.
The information “level to a task of the vagus nerve inflammatory reflex in suppressing cytokine storm throughout COVID-19,” coauthor Dr. Kevin Tracey of The Feinstein Institutes for Medical Analysis in Manhasset, New York, mentioned in a press release.
Direct electrical stimulation of the vagus nerve is thought to enhance a wide range of ailments.
“Famotidine, a well-tolerated oral drug, may provide a further methodology” of activating the vagus nerve to scale back inflammatory protein technology and ensuing tissue harm in COVID-19 and different ailments, the researchers concluded.
—Reporting by Nancy Lapid; Modifying by Invoice Berkrot
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