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The next is a abstract of some latest research on COVID-19. They embody analysis that warrants additional research to corroborate the findings and that has but to be licensed by peer assessment.
Excessive-pressure oxygen therapy could assist lengthy COVID
Sufferers with lengthy COVID might even see some enchancment after respiratory pure oxygen in a high-air-pressure surroundings, in keeping with information from a small Israeli trial.
Researchers randomly assigned 73 sufferers with post-COVID signs lasting at the least three months to obtain hyperbaric oxygen remedy (HBOT) or a sham therapy.
Sufferers within the HBOT group spent 40 classes respiratory pure oxygen in a chamber by which the air stress was two-to-three occasions greater than regular, permitting the lungs to obtain extra oxygen than they usually would.
Shortly after the final therapy, the HBOT group confirmed “vital enchancment” in comparison with the sham group in considering expertise, vitality, sleep, psychiatric signs, and ache, in keeping with a report revealed on Tuesday in Scientific Studies.
Symptomatic enchancment was related to magnetic resonance imaging proof of structural and purposeful mind therapeutic and improved supply of oxygen-carrying blood to the mind, the researchers stated.
HBOT is commonly used to deal with wounds that aren’t therapeutic properly and has lately been examined as a therapy for traumatic mind harm, however that is the primary randomized trial to check it for lengthy COVID. Bigger research are wanted to verify the findings and to determine sufferers who may profit, the researchers stated.
Earlier Omicron an infection could defend in opposition to BA.4/BA.5
Younger and middle-aged adults who have been contaminated with earlier variations of the Omicron variant of the coronavirus are more likely to have “sturdy” safety in opposition to reinfection with the at present dominant Omicron BA.4 and BA.5 subvariants, researchers say.
That won’t be the case in the event that they have been contaminated with a variant that circulated earlier than Omicron, nevertheless, in keeping with a research from Qatar. Researchers there discovered that after taking vaccination standing under consideration, an infection with a pre-Omicron model of SARS-CoV-2 seemed to be solely 15.1% efficient at stopping a symptomatic BA.4/BA.5 reinfection and 28.3% efficient at stopping any BA.4/BA.5 reinfection.
A earlier Omicron an infection, nevertheless, was 76.1% efficient in opposition to symptomatic BA.4/BA.5 reinfection and 79.7% efficient in opposition to any BA.4/BA.5 reinfection.
The research didn’t assess the severity of reinfection. In a report posted on medRxiv on Tuesday forward of peer assessment, the researchers level out that the findings is probably not relevant in older folks, on condition that in Qatar solely 9% of the residents are older than 50.
The research additionally confirmed that safety from infections with earlier pre-Omicron variants was weaker in opposition to BA.4/BA.5 than it was in opposition to BA.1/BA.2, “indicating that these two new variants have larger capability to flee the immune-system response,” stated research chief Laith Jamal Abu Raddad of Weill Cornell Drugs-Qatar.
COVID-19 vaccines linked with longer intervals for some girls
COVID-19 vaccination could also be related to short-term lengthening of the menstrual cycle for some girls, in keeping with a brand new research.
The findings are drawn from 3,858 feminine nurses in the USA and Canada who’ve been filling out questionnaires about their intervals twice a 12 months since 2011. As of December 2021, 91% of them had been vaccinated in opposition to the coronavirus. Earlier than the pandemic, 15% reported irregular cycles; that rose to 22.7% in 2021, the researchers reported on Wednesday within the American Journal of Obstetrics & Gynecology. Vaccinated girls had a 54% greater danger of elevated cycle size in comparison with unvaccinated girls, no matter vaccine kind and even after taking pandemic stress and health-related components under consideration, the report stated. On nearer evaluation, vaccination was solely related to change to longer cycles within the first six months after vaccination and amongst girls whose cycles have been brief, lengthy or irregular earlier than vaccination, not amongst girls with regular size, common cycles.
“A traditional menstrual cycle is characterised by tightly regulated inflammatory and immune mediators” that could be quickly affected by the physique’s immune response to the vaccines, the researchers stated. They name for monitoring of “menstrual cycle well being in vaccine scientific trials and elevated consideration to sex-based variations in vaccine response.”
—Reporting by Nancy Lapid; Enhancing by Invoice Berkrot
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